Medicine & Health Sciences - Pharmacology & Toxicology

List of Courses

PHTX601
PHTX603
PHTX604
PHTX607
PHTX608
PHTX609
PHTX610
PHTX611
PHTX612
PHTX613
PHTX614
PHTX615
PHTX616
PHTX617
PHTX618
PHTX619
PHTX620
PHTX621
PHTX622
PHTX623
PHTX624


* All credit hours are based on the current term, this may vary for previous terms.

PHTX601 - General Systemic Pharmacology (2 credit hours)
This course is designed to teach graduate students the effects of drugs on different organ systems. The drugs acting on major organ systems will be reviewed (the autonomic nervous system and the cardio-vascular, respiratory, kidney, endocrine and nervous systems). Different methods will be discussed to define the mechanisms of drug action and how drugs influence the different systems in the human body. This course will be in a Seminar format as well as computer based practical programs.

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Semester: Fall Spring Go To Index


PHTX603 - Neurotransmitters (2 credit hours)
Neurotransmitters in Health and Disease : This course is devoted to exploring the biosynthesis, inactivation, receptors, and signaling mechanisms of neurotransmitters and chemical mediators including GABA, glutamate, acetylcholine, catecholamines, purines, peptides, prostaglandins, and histamines. In brief, the molecular and cellular aspects of receptor mechanisms as well as signaling pathways, and effector systems will be discussed. The teaching format includes Seminars and discussions.

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Semester: Fall Spring Go To Index


PHTX604 - Mol. Principles of Organ Tox. (2 credit hours)
Molecular Principles of Organ Toxicity: This course is designed to teach graduate students the mechanisms involved in the actions of drugs and toxins on the target organs. The course will focus on molecular mechanism of chemically-induced toxicity to specific organs in the mammalian species. It describes the principles of cellular and molecular mechanisms of organ system toxicology with emphasis on developmental toxicology, carcinogenesis, immune toxicity, renal toxicity, hepatic toxicity and neurotoxicity. The effects of toxins on respiratory, blood, cardiac, skin and eyes at the cellular level will also be addressed in this course. Various factors affecting toxicity to each particular organ will be studied. This course will be in a Seminar format as well as small focus group discussion.

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Semester: Spring Go To Index


PHTX607 - Pathophysiology&Theraputics I (3 credit hours)
Pathophysiology & Therapeutics I: This course focuses on the pharmacotherapy in disease management. It covers Infectious Diseases, Multiple Sclerosis Alzheimer?s Disease, Parkinson's disease, Seizure Disorders, Depression, anxiety Disorders and personality disorders. Emphasis will be placed on the integration of pathophysiology, pharmacology and therapeutics to for appropriate care plans. These plans will include rationale for drug use, selection and dosing regimens, expected outcomes of drug therapy, key monitoring parameters, clinically important drug-drug or drug-disease interactions, counseling and compliance issues. The class fonnat inc1udes online reading assignments, study guides, and assignments, interactive Internet-based lectures and case studies.

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Semester: Spring Go To Index


PHTX608 - Pathophysiology&TherapeuticsII (3 credit hours)
Pathophysiology & Therapeutics II : This course focuses on the phannacotherapy in disease state management of Hypertension, Ischemic Heart Disease, Myocardial Infarct, Heart Failure, Stroke, Anticoagulation, Upper GI Disorders, Asthma & COPD, and Renal Diseases. Emphasis will be placed on the integration of pathophysiology, pharmacology and therapeutics to devise appropriate pharmacy care plans. These plans will include rationale for drug use, selection and dosing regimens, expected outcomes of drug therapy, key monitoring parameters, clinically important drug-drug or drug-disease interactions, counseling and compliance issues. The class format includes online reading assignments, study guides, and assignments, interactive Internet-based lectures and case studies.

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Semester: Spring Go To Index


PHTX609 - Pathophysiology&Therap. III (3 credit hours)
Pathophysiology & Therapeutics III : This course focuses on the phannacotherapy and the management of diseases and conditions including .Hormone Replacement, Osteoporosis, Rheumatoid and Osteoarthritis, Lipid Disorders and Diabetes. Emphasis will be placed on the integration of pathophysiology, pharmacology and therapeutics to devise appropriate pharmacy care plans. These plans will include rationale for drug use, selection and dosing regimens, expected outcomes of drug therapy, key monitoring parameters, clinically important drug-drug or drug-disease interactions, counseling and compliance issues. The class fonnat includes online reading assignments, study guides, assignments, interactive Internet-based lectures and case studies

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Semester: Spring Go To Index


PHTX610 - Pathophysiology&Therap. IV (3 credit hours)
Pathophysiology & Therapeutics IV : This course focuses on the pharmacotherapy and the role of the pharmacist in disease state management of diseases and conditions including Cancer, Critical Care and Infectious Diseases. Emphasis will be placed on the integration of pathophysiology, pharmacology and therapeutics to devise appropriate pharmacy care plans. These plans will include rationale for drug use, selection and dosing regimens, expected outcomes of drug therapy, key monitoring parameters, clinically important drug-drug or drug-disease interactions, counseling and compliance issues. The class format includes online reading assignments, study guides, assignments, interactive Internet?based lectures and case studies

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Semester: Spring Go To Index


PHTX611 - Poisoning & Drug Toxicity (2 credit hours)
Poisoning & Drug Toxicity: This course is designed to familiarize postgraduate Pharnill students with the concepts of clinical toxicology, poisoning and drug toxicity in application to patient care. The course will review the basics of clinical toxicology and managing toxic exposures. It will describe the importance of patient history, signs and symptoms and in the diagnosis, management and foHow-up of poisoning conditions. It also emphasizes obtaining history, appropriate investigation and supportive care in poisoning cases and toxicological exposures. The course covers clinical steps in recognition, evaluation, assessment and treatment of various toxicological syndromes. It identifies life support measures relevant to treatment of poisoned patients and critically ill individuals. The seminars are structured and followed-up by practical case to help in understanding the theory and practice of clinical toxicology. This course will be in a seminar format as well as group discussions and cases

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Semester: Spring Go To Index


PHTX612 - Pharmaceutical Care (2 credit hours)


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Semester: All Go To Index


PHTX613 - Ambulatory Care (2 credit hours)


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Semester: All Go To Index


PHTX614 - General Internal Medicine (2 credit hours)


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Semester: All Go To Index


PHTX615 - Drug Information (2 credit hours)


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Semester: All Go To Index


PHTX616 - Adult Oncology (2 credit hours)


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Semester: All Go To Index


PHTX617 - Pediatric Oncology (2 credit hours)


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Semester: All Go To Index


PHTX618 - Infectious Diseases (2 credit hours)


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Semester: All Go To Index


PHTX619 - Advances in Pharmacology (1 credit hours)
This reading course is designed to promote self-learning of graduate students regarding general principles of drugs closely related to their Ph.D. or Master thesis. The topics will be chosen mainly by graduate students and expected to be related to recent pharmacological progress in treatment modalities

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Semester: Spring Go To Index


PHTX620 - Pediatrics (2 credit hours)
The general pediatrics rotation is 4 week rotation for PharmD candidates. The focus of this rotation is the provision of complete pharmaceutical care services to the pediatric patient populations. The patients range in age from newborns to young adults. In addition to general medical cases, other admissions include transfers Intensive care Units and children receiving chemotherapy. Pharmacists will be required to provide the following services: • Daily patient profile review with identification and resolution of patient medication problems • Daily rounding with the general pediatrics service • Pharmacokinetic consultations • Drug information services • Coordination of medication ordering and distribution problems, working in conjunction with the inpatient pediatric pharmacy • Documentation of activities through the intervention pathway Core content to be addressed through patient case presentations and topic review sessions include: • Management of sepsis in young children • Therapeutic drug monitoring and pharmacokinetic differences in children • Fluid balance and electrolyte replacement • Normal growth and development • Medication error prevention and the development of pediatric clinical services

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Semester: All Go To Index


PHTX621 - Critical Care (2 credit hours)
The 4 week Adult Intensive Care rotation allows for the provision of pharmaceutical care to complex critically ill adults with multiple medical problems. Exposure to a variety of disease states and pharmacotherapy management experiences occurs during the rotation. The pharmacist must assume responsibility and accountability for all pharmacotherapy management issues for their assigned patients. Generally speaking, they must provide the following pharmaceutical care services: patient profile review with medication/therapy problem identification and resolution; assistance with medication order entry, order review and order clarification; rounding with Adult Intensive Care multidisciplinary team; pharmacokinetic and nutritional support consults; responses to drug information requests; good communication and interaction with nurses, physicians, and support specialists; and coordination of distribution problems not resolved by in¬patient pharmacy. Core content which will be covered via patient experiences, discussions of reading materials, and/or case presentations includes a review of: • Hemodynamic support using isotropic / vasoactive agents • Analgesia, sedation, and neuromuscular blockade • Pharmacokinetics in critically ill patients • Sepsis/septic shock/systemic inflammatory response syndrome (SIRS) • Multiple organ failure and oxygen delivery in critically ill patients • Fluid and electrolyte balance replacement in critically ill patients • Acute renal failure/uremic bleeding/acid-base disturbances • Disseminated intravascular coagulation (DIC) • Variety of infectious diseases (a few examples- Catheter-Related Blood Stream Infections, Hospital and Ventilator Associated Pneumonia, Community-Acquired Pneumonia, etc.) • Acute respiratory distress syndrome (ARDS) • Acute alcohol withdrawal • Diabetic ketoacidosis (DKA) • Status epilepticus • Heparin Induced Thrombocytopenia • Stroke • Hypertensive emergency • Acute gastrointestinal bleeding • Acute Asthma and COPD exacerbation • Acute Toxicity (Tricyclic antidepressants, acetaminophen, miscellaneous) • lCU prophylaxis issues: Gastrointestinal stress ulcer prophylaxis, venous thrombosis prophylaxis

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Semester: All Go To Index


PHTX622 - Emergency Medicine (2 credit hours)
The emergency Medicine rotation is a 4 week rotation for PharmD candidates. This rotation allows the provision of pharmaceutical care to patients attending pediatric and adults Emergency Medicine Service. The focus of the rotation is the management of drug therapy in patients with multiple medical problems, surgical emergencies and toxicological exposures. The complete spectrum of pharmaceutical care services experienced during the rotation includes: • Daily patient profile review with identification and resolution of patient medication problems • Assistance with medication order entry, order review and order clarification • Rounding with the Emergency Medicine Physician Teams • Providing pharmacokinetic consults • Providing drug information services to members of the healthcare team • Monitoring and reporting Adverse Drug Reactions • Interaction with physicians and other healthcare providers • Coordination of distribution problems not resolved by in-patient pharmacy Core content which will be covered via patient experiences, discussions of reading materials, and/or case presentations includes a review of: • Hemodynamic support in emergences (supporting respiration, cardiovascular and CNS functions) • Analgesia, sedation, and neuromuscular blockade • Emergency seizures • Cardiac arrest • Hypertensive emergency • Sepsis/septic shock/systemic inflammatory response syndrome (SIRS) • Variety of infectious diseases (Pneumonia, Meningitis) • Organ failure and oxygen delivery • Respiratory failure & Acute respiratory distress syndrome (ARDS) • Fluid and electrolyte balance & replacement, acid-base disturbances • Acute renal failure, uremic bleeding • Disseminated intravascular coagulation (DIC) • Asthma • Acute COPD exacerbation • Diabetic ketoacidosis (DKA.) • Hypoglycemia • Throtoxicosis • Acute bleeding • Acute alcohol withdrawal • Acute toxicity (tricyclic antidepressants, acetaminophen, miscellaneous) • Pharmacokinetics in emergency conditions

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Semester: All Go To Index


PHTX623 - Research Project (4 credit hours)
Research might include chart review, epidemiological studies of common illnesses or involvement in human clinical trials. Student supervision will follow the standard procedures established by UAE University Office of Research & Graduate Studies and each hospital's patient protection protocols.

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Semester: All Go To Index


PHTX624 - ModernMed.Chemistry&DrugDesign (1 credit hours)
A broad variety of medicinal chemistry approaches can be used for the identification of hits, generation of leads, as well as to accelerate the development of high quality drug candidates. Structure-based drug design (SBDD) methods are becoming increasingly powerful, versatile and more widely used. This course demonstrates current developments in structure-based virtual screening and receptor-based pharmacophores, highlighting achievements as well as pharmacodynamics and pharmacokinetic challenges, along with the value of structure-based lead optimization, with emphasis on recent examples of successful applications for the identification of novel active compounds.

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Semester: Fall Spring Go To Index